MAST®ALEX-MRSA (RST501); for the detection of penicillin binding protein 2’ (PBP2’) and confirmation of Methicillin resistant Staphylococcus aureus (MRSA)

The continuing presence of MRSA worldwide requires appropriate management and treatment of MRSA remains important. Research has indicated it is important to either directly detect the mecA gene coding for methicillin resistance or its product PBP2’.

Antimicrobial therapy is critical in such infections but conventional methods for identifying MRSA, such a susceptibility testing, are not always reliable since phenotypic expression of methicillin resistance is known to be heterogeneous, depending on such factors as incubation time, temperature, NaCL concentration etc. Some methods for detecting the mecA gene such as Polymerase Chain Reaction (PCR) take time and can prove to be expensive for confirming the presence of MRSA on routine testing.

MAST®ALEX-MRSA (RST501) is a sensitive and rapid slide agglutination assay which detects PBP2’ present in MRSA, using latex sensitised with a monoclonal antibody directed against PBP2’, proving itself to be useful in the clinical diagnostic confirmation of MRSA for epidemiological and research purposes.

MAST®ALEX-MRSA (RST501) is presented in a convenient latex format, with clear and easy to read results, allowing for a rapid turn round time of 5 to 10 minutes per sample, proving itself to be cost effective and ideal for using in the screening or diagnostic scenario. It is sensitive as uses a monoclonal antibody directed against the PBP2’. It is presented in a user friendly format with all reagents colour coded, with sufficient reagents for 48 tests.